(TETRAHYDROFURAN-3-YL)BORONIC ACID PINACOL ESTER

(TETRAHYDROFURAN-3-YL)BORONIC ACID PINACOL ESTER - Names and Identifiers

Name	4,4,5,5-tetramethyl-2-(tetrahydro-3-furanyl)-1,3,2-Dioxaborolane
Synonyms	Tetrahydrofuran-3-boronic acid picol ester TETRAHYDROFURAN-3-BORONIC ACID PINACOL ESTER 4,4,5,5-Tetramethyl-2-(tetrahydrofuran-3-yl) (TETRAHYDROFURAN-3-YL)BORONIC ACID PINACOL ESTER 4,4,5,5-tetramethyl-2-(oxolan-3-yl)-1,3,2-dioxaborolane 4,4,5,5-tetramethyl-2-(tetrahydro-3-furanyl)-1,3,2-Dioxaborolane 4,4,5,5-Tetramethyl-2-(Tetrahydro-3-Furanyl)-1,3,2-Dioxaborolane 1,3,2-Dioxaborolane, 4,4,5,5-tetramethyl-2-(tetrahydro-3-furanyl)-
CAS	331958-90-8
InChI	InChI=1S/C10H19BO3/c1-9(2)10(3,4)14-11(13-9)8-5-6-12-7-8/h8H,5-7H2,1-4H3

(TETRAHYDROFURAN-3-YL)BORONIC ACID PINACOL ESTER - Physico-chemical Properties

Molecular Formula	C10H19BO3
Molar Mass	198.07
Density	0.99±0.1 g/cm3(Predicted)
Boling Point	230.6±33.0 °C(Predicted)
Appearance	Liquid
Color	Colorless to pale yellow
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C

(TETRAHYDROFURAN-3-YL)BORONIC ACID PINACOL ESTER - Introduction

4,4,5,5-tetramethyl-2-(tetrahydro-3-furanyl)-1,3,2-Dioxaborolane is an organic compound with the chemical formula C9H17BO3. The following is an introduction to its nature, use, formulation and safety information:

Nature:
-Appearance: colorless liquid
-Melting point:-76 ° C
-Boiling point: 155-157 ° C
-Density: 0.99 g/mL

Use:
- 4,4,5,5-tetramethyl-2-(tetrahydro-3-furanyl)-1,3,2-Dioxaborolane is often used as an important reagent in organic synthesis.
-It can be used for the preparation of catalysts, such as the synthesis of Dosimetric catalysts and catalytic asymmetric hydrogenation reactions.
-It can also be used for other synthetic reactions in organic chemistry, such as carbonyl addition reactions, asymmetric etherification reactions, etc.

Method:
The preparation of 4,4,5,5-tetramethyl-2-(tetrahydro-3-furanyl)-1,3,2-Dioxaborolane can usually be carried out by the following steps:
1. Dissolve tetrahydrofuran in dichloromethane.
2. Triphenylphosphine and phenyl borate are added to the solution and heated for reaction.
3. Further heat to reflux, and use detergent to extract the reaction product from the solution.
4. After purification by distillation and crystallization, 4,4,5,5-tetramethyl-2-(tetrahydro-3-furanyl)-1,3,2-Dioxaborolane is obtained.

Safety Information:
- 4,4,5,5-tetramethyl-2-(tetrahydro-3-furanyl)-1,3,2-Dioxaborolane is an organic solvent with flammable and irritating properties.
-During use, necessary safety measures should be taken, such as wearing appropriate protective gloves and glasses, and ensuring good ventilation.
-In case of accidental contact or inhalation, wash the affected area immediately and seek medical help.
-During storage, 4,4,5,5-tetramethyl-2-(tetrahydro-3-furanyl)-1,3,2-Dioxaborolane should be stored in a dry and cool place, keep fire and oxidizers away.

Last Update：2024-04-10 22:29:15